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ORIGINAL ARTICLE
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Association between corneal biomechanical parameters and myopic refractive errors in young Indian individuals


1 Department of Cornea and Refractive Surgeries, Kenia Eye Hospital, Mumbai, Maharashtra, India
2 Kenia Foundation, Mumbai, Maharashtra, India
3 Kenia Medical and Research Foundation, Mumbai, Maharashtra, India

Correspondence Address:
Onkar H Pirdankar,
Kenia Medical and Research Foundation, Mumbai, Maharashtra
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjo.tjo_15_19

PURPOSE: To report corneal biomechanical parameters in young myopic Indian individuals. METHODS: It is a retrospective study where young myopic individuals aged between 19 and 36 years who have undergone corneal biomechanics assessment using Corvis ST between January 2017 and December 2017 were enrolled. Individuals with central corneal thickness (CCT) <500 microns, intraocular pressure (IOP) >21 mmHg, history of any systemic and ocular disease, any previous ocular surgery, high astigmatism, corneal disease such as keratoconus, poor scans quality, and individuals with any missing data were also excluded. Corneal biomechanical parameters were noted in mild to moderate and high myopia. RESULTS: We analyzed the 266 eyes of 266 myopic individuals, of which 167 and 99 eyes had mild to moderate and high myopia, respectively. All the individuals were matched for age, IOP, and CCT (P > 0.05). Twenty-three of 32 parameters were similar in different degrees of myopia whereas 9 parameters were significantly different in high myopes as compared to low to moderate myopes. First applanation (A1) parameters and Vinciguerra screening parameters were similar in both the groups (P > 0.05). Second applanation (A2) parameters were similar in both the groups (P > 0.05) except A2 time, A2 deformation, amplitude (DA) (P < 0.05). Highest concavity (HC) parameters were significantly different in both the groups (P < 0.05) except HCDA, HC deflection length, and HC delta arc length (P > 0.05). CONCLUSIONS: High myopic eyes showed a significantly higher maximum deflection amplitude, lesser A2 time and HC time, less A2DA, smaller HC radius than mild to moderate myopia indicating softer, more deformable corneas. However, better predictor of corneal biomechanics such as Stiffness parameters at A1 (SPA1), DA ratio max, integrated radius, and Corvis Biomechanical Index were similar among both the groups of myopia.


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