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  Indian J Med Microbiol
 

Figure 1: Histology and immunohistochemical detection of SM22 in an injured lens. (a) Frames A–D show hematoxylin and eosin-stained histology of a puncture-injured lens in control (A, C) and fasudil hydrochloride-treated mice (B, D) on day 5 (A, B) and day 10 (C, D), respectively. Frames A'–D' indicate the positive expression of SM22 expression (black arrows) in Frames A–D, respectively. The cells in the clusters were considered to be myofibroblasts derived from lens epithelial cells through epithelial-mesenchymal transition. Bar, 100 μm. (b) The distance between each edge (arrows) of the broken capsule was measured and statistically analyzed. The distance between each edge of the broken capsule was statistically significantly larger on both days 5 and 10 in fasudil group of mice as compared with control mice. Significant *P <0.05 by Mann-Whitney U test

Figure 1: Histology and immunohistochemical detection of SM22 in an injured lens. (a) Frames A–D show hematoxylin and eosin-stained histology of a puncture-injured lens in control (A, C) and fasudil hydrochloride-treated mice (B, D) on day 5 (A, B) and day 10 (C, D), respectively. Frames A'–D' indicate the positive expression of SM22 expression (black arrows) in Frames A–D, respectively. The cells in the clusters were considered to be myofibroblasts derived from lens epithelial cells through epithelial-mesenchymal transition. Bar, 100 μm. (b) The distance between each edge (arrows) of the broken capsule was measured and statistically analyzed. The distance between each edge of the broken capsule was statistically significantly larger on both days 5 and 10 in fasudil group of mice as compared with control mice. Significant *<i>P</i> <0.05 by Mann-Whitney U test