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Year : 2021  |  Volume : 11  |  Issue : 1  |  Page : 97-100

Optic nerve head plasmacytoma as a manifestation of multiple myeloma

1 Department of Ophthalmology, Emory University, Atlanta, GA, USA
2 Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
3 Department of Ophthalmology; Department of Pediatrics, Emory University, Atlanta, GA, USA

Correspondence Address:
Kaitlin P Sandor
Emory Eye Center, 1365-B Clifton Road, NE, Atlanta, GA 30322
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjo.tjo_81_20

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Extramedullary disease in multiple myeloma is uncommon and associated with a poorer prognosis. Extramedullary disease involving the orbit is even more unusual, with optic nerve involvement being rare. We describe an optic nerve head plasmacytoma in a 45-year-old female in the setting of systemic relapsed, refractory IgA kappa multiple myeloma. The case highlights the importance of keeping extramedullary disease spread in the differential for vision loss in a patient with a history of multiple myeloma. In addition, it describes an unusual location for presentation of extramedullary disease, the optic nerve head, which has rarely been described.

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